Biogeochemical characteristics and ecological risk assessment of pharmaceutically active compounds (PhACs) in the surface seawaters of Jiaozhou Bay, North China
| Autor: | Ning Li, Quancai Peng, Huamao Yuan, Jinming Song, Qian Zhang, Xianmeng Liang, Xuegang Li, Liqin Duan |
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| Rok vydání: | 2019 |
| Předmět: |
Pollution
Aquatic Organisms China Biogeochemical cycle 010504 meteorology & atmospheric sciences Health Toxicology and Mutagenesis media_common.quotation_subject 010501 environmental sciences Toxicology Risk Assessment 01 natural sciences chemistry.chemical_compound Nutrient Rivers Tandem Mass Spectrometry medicine Seawater Carprofen 0105 earth and related environmental sciences media_common Ecology Chemistry General Medicine Phosphate Lincomycin Bays Environmental chemistry Bay Water Pollutants Chemical Environmental Monitoring medicine.drug |
| Zdroj: | Environmental Pollution. 255:113247 |
| ISSN: | 0269-7491 |
| Popis: | The occurrence and distribution of 168 pharmaceutically active compounds (PhACs) in the surface seawater of Jiaozhou Bay (JZB) were investigated using ultra-high-performance liquid chromatography in tandem with a triple-quadrupole mass spectrometer equipped with an electrospray ionization source (UHPLC-ESI-MS-MS). Thirty-six compounds were detected, and 17 of these compounds were first detected in seawater, including sulfabenzamide, sulphacetamide, cephalonium, desacetyl-cefotaxime, cefminox, cefotaxime, cephradine, cefazolin, carprofen, nabumetone, glibenclamide, glimepiride, glipizide, prednisone, fluoromethalone, diazepam and amantadine. The total concentration of PhACs in the surface seawater ranged from 23.6 ng/L to 217 ng/L. The compounds found at the highest mean concentrations included amantadine (24.7 ng/L), lincomycin (8.55 ng/L), carprofen (8.30 ng/L), and tetracycline (7.48 ng/L). The PhAC concentration was higher in the inner bay than in the outside of the bay. In the inner bay, the eastern district showed higher concentrations of PhACs than the western district. Input from the Licun River may be the primary source of pollution. A statistically significant positive correlation was observed between nutrients and PhACs in seawater. Phosphate can be used to indicate the distribution of PhACs in JZB. Based on the individual risk quotient (RQ) values, lincomycin and ofloxacin posed high risks to the relevant aquatic organisms in JZB, especially in the eastern parts. Regular monitoring is required to evaluate the levels of PhACs as they are constantly released into JZB. |
| Databáze: | OpenAIRE |
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