Nitrate-NRT1.1B-SPX4 cascade integrates nitrogen and phosphorus signalling networks in plants
| Autor: | Xiahe Huang, Chengcai Chu, Sai Kang, Yiqin Wang, Yangwen Qian, Junpeng Xie, Zhimin Jiang, Zhihua Zhang, Yahong Qiu, Lianhe Zhang, Stanislav Kopriva, Bin Hu, Yongqiang Liu, Wei Wang, Feifei Yu, Linchuan Liu, Aifu Li, Xiaokai Gao, Shouyun Cao, Yingchun Wang, Qi Xie |
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| Rok vydání: | 2018 |
| Předmět: |
0106 biological sciences
0301 basic medicine Nitrogen Anion Transport Proteins Repressor Plant Science 01 natural sciences 03 medical and health sciences chemistry.chemical_compound Nitrate Transcription (biology) Transcription factor Plant Proteins Oryza sativa Nitrates biology Oryza Phosphorus Phosphate Cell biology Ubiquitin ligase 030104 developmental biology chemistry biology.protein Phosphorus utilization 010606 plant biology & botany Signal Transduction |
| Zdroj: | Nature plants. 5(4) |
| ISSN: | 2055-0278 |
| Popis: | To ensure high crop yields in a sustainable manner, a comprehensive understanding of the control of nutrient acquisition is required. In particular, the signalling networks controlling the coordinated utilization of the two most highly demanded mineral nutrients, nitrogen and phosphorus, are of utmost importance. Here, we reveal a mechanism by which nitrate activates both phosphate and nitrate utilization in rice (Oryza sativa L.). We show that the nitrate sensor NRT1.1B interacts with a phosphate signalling repressor SPX4. Nitrate perception strengthens the NRT1.1B-SPX4 interaction and promotes the ubiquitination and degradation of SPX4 by recruiting NRT1.1B interacting protein 1 (NBIP1), an E3 ubiquitin ligase. This in turn allows the key transcription factor of phosphate signalling, PHR2, to translocate to the nucleus and initiate the transcription of phosphorus utilization genes. Interestingly, the central transcription factor of nitrate signalling, NLP3, is also under the control of SPX4. Thus, nitrate-triggered degradation of SPX4 activates both phosphate- and nitrate-responsive genes, implementing the coordinated utilization of nitrogen and phosphorus. |
| Databáze: | OpenAIRE |
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