Long term results of percutaneous balloon valvoplasty of congenital aortic stenosis: independent predictors of outcome
| Autor: | Tax P, Jan Škovránek, O Reich, Viktor Tomek, H Bartáková, Vit Razek, J Gilík, V Chaloupecký, Jan Marek |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2004 |
| Předmět: |
musculoskeletal diseases
Adult congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty Percutaneous Adolescent genetic structures Aortic Valve Insufficiency Disease-Free Survival Catheterization Cohort Studies Bicuspid aortic valve Restenosis Recurrence Internal medicine Mitral valve Humans Medicine Hospital Mortality cardiovascular diseases Cardiac skeleton Child business.industry Infant Newborn Editorials Congenital Heart Disease Infant Aortic Valve Stenosis medicine.disease Surgery Treatment Outcome medicine.anatomical_structure Ventricle Child Preschool Aortic valve stenosis Retreatment Cardiology Balloon dilation cardiovascular system Cardiology and Cardiovascular Medicine business Follow-Up Studies |
| Popis: | Objective: To evaluate long term results and independent predictors of outcome of aortic valvoplasty. Design: Retrospective follow up study. Independent predictors of outcome identified by multiple logistic regression. Setting: Tertiary referral centre. Patients: 269 consecutive patients treated at the median age of 8 months (0–23 years): 80 (30%) under 4 weeks, 59 (22%) between 4 weeks and 1 year, and 130 (48%) over 1 year. The follow up period was up to 14.8 years (median 5.3, in survivors 6.4 years). Interventions: Percutaneous balloon valvoplasty with mean (SD) balloon to annulus ratio 0.97 (0.08). Main outcome measures: Restenosis ⩾ 70 mm Hg, grade 3 aortic insufficiency, cusps disruption, surgery, death, and valvoplasty failure (significant restenosis or insufficiency or surgery or death). Results: The mortality rate was 10.4% (n = 28), the restenosis rate was 16.7% (n = 45), significant insufficiency developed in 22.3% (n = 60), surgery was needed in 20.1% (n = 54), and “valvoplasty failure” occurred in 41.6% (n = 112) patients. Mean (SEM) survival probability 14.4 years after the procedure was 0.89 (0.02) and mean (SEM) probability of surgery-free survival was 0.50 (0.08). The independent predictors were as follows. For restenosis: small aortic annulus; for cusp disruption: large aortic annulus; for insufficiency: bicuspid aortic valve; for need for surgery: bicuspid aortic valve; for death: small aortic annulus, low left ventricular shortening fraction, and low sequential number of the valvoplasty; and for valvoplasty failure: small aortic annulus, bicuspid aortic valve, and high grade of mitral insufficiency. Conclusion: Independent predictors of unfavourable outcome are small aortic annulus, bicuspid aortic valve, poor function of left ventricle or mitral valve, and limited operator experience. |
| Databáze: | OpenAIRE |
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