A contribution to neuromorphic engineering: neuromodulation implemented through photochromic compounds maintained out of equilibrium by UV–visible radiation
| Autor: | Pier Luigi Gentili, Beatrice Bartolomei, B. Mark Heron |
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| Rok vydání: | 2020 |
| Předmět: |
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Computer science Network Context (language use) 01 natural sciences Signal 03 medical and health sciences Photochromism Artificial Intelligence Autapses Far-from-equilibrium Neurons 0103 physical sciences 010303 astronomy & astrophysics General Environmental Science Electronic circuit 0303 health sciences Artificial neural network Visible radiation Neuromodulation (medicine) 030301 anatomy & morphology Neuromorphic engineering General Earth and Planetary Sciences General Agricultural and Biological Sciences Biological system |
| Zdroj: | Rendiconti Lincei. Scienze Fisiche e Naturali. 31:39-52 |
| ISSN: | 1720-0776 2037-4631 |
| DOI: | 10.1007/s12210-020-00869-y |
| Popis: | Neuromodulation is the alteration of neuronal and synaptic properties in the context of neuronal circuits. It allows anatomically defined circuits to produce multiple outputs reconfiguring networks into different functional circuits. In this work, neuromodulation is mimicked using a solution of two direct photochromic compounds, a naphthopyran and a spirooxazine, which are models of phasic excitable neurons, sensitive to UV radiation. When the system, constituted by the two photochromic compounds, receives a UV signal, it behaves as a recurrent network with mutual inhibitory actions. The network responds to different UV wavelengths by changing its photo-excitability, synaptic strength, wiring of the circuit, and dynamics. These results contribute to the development of neuromorphic engineering. They will promote the design of artificial neural networks with a larger number of nodes, communicating through optical signals. These networks will be the essential ingredients of the new-generation brain-like computing machines complementing current electronic computers. |
| Databáze: | OpenAIRE |
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