More attention should be paid to adult gastric cancer patients younger than 35 years old: extremely poor prognosis was found
| Autor: | Miao Zhen Qiu, Xiang Lei Yan, Wen Long Guan, Lu Ping Yuan, Dajun Yang |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Extremely Poor
medicine.medical_specialty Poor prognosis Pediatrics Multivariate analysis Tumor size business.industry Young Cancer Prognosis medicine.disease Clinic-pathologic features 03 medical and health sciences Young age Age 0302 clinical medicine Oncology 030220 oncology & carcinogenesis Epidemiology Medicine 030211 gastroenterology & hepatology Stage (cooking) Gastric cancer business Research Paper |
| Zdroj: | Journal of Cancer |
| ISSN: | 1837-9664 |
| Popis: | Purpose: Several studies have reported controversial results about prognosis of gastric cancer in young age patients. The difference may partially result from variable definitions of young age. The aim of this study was to find out the relation between age and prognosis of gastric cancer patients, and to analyze the clinicopathological features and prognostic factors in young gastric cancer patients. Methods: Data queried for this analysis included GC patients from the Surveillance, Epidemiology, and End Results Program database from 1973 to 2014. Gastric cancer patients (N=79,505) diagnosed with an age≥18 were included. By combining patients with similar prognosis, we figured out 3 cutoff values of age, 35 years old, 65 years old and 75 years old. We divided patients into 4 groups: young age patients: 18-34 years; middle-age patients: 35-64 years; elderly patients: 65-74 years; extremely elderly patients: >74 years. GC patients from Sun Yat-sen University Cancer Center (SYSUCC) were used as external validation data. Results: The clinicopathological features of young age gastric cancer patients included: poor-differentiated, diffuse type of cancer, and advanced stage at diagnosis. The median survival of patients |
| Databáze: | OpenAIRE |
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