Qualitative Immunoglobulin Abnormalities in HIV-Positive Patients: Long-Term Follow-Up
| Autor: | Marie-Christine Mazeron, F. Pontet, X. Gue, S. Alain, M.-J. Sanson-Le Pors |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Adult
Male Immunofixation Clinical Biochemistry Population Immunoglobulins HIV Infections Immunoelectrophoresis Immunoglobulin E Age Distribution medicine Humans Sex Distribution education Survival analysis education.field_of_study biology medicine.diagnostic_test Biochemistry (medical) General Medicine Middle Aged Prognosis Survival Analysis Polyclonal antibodies HIV-2 Cohort Immunology HIV-1 biology.protein Female Antibody Follow-Up Studies |
| Zdroj: | cclm. 36:493-496 |
| ISSN: | 1434-6621 |
| DOI: | 10.1515/cclm.1998.082 |
| Popis: | We studied the immunoglobulins of a cohort of 212 HIV-positive patients followed-up for 13 years. The qualitative study of immunoglobulins by immunoelectrophoresis and immunofixation distinguished three groups of patients: those with monoclonal immunoglobulins, those with minor abnormalities of immunoglobulins and those with polyclonal immunoglobulins. We characterized these groups according to age, sex, immunoglobulin isotypes, and survival curves. The results show that this population of immunoglobulinopathies has distinctive characteristics. In particular, the presence of immunoglobulin abnormalities has no significant prognostic value. |
| Databáze: | OpenAIRE |
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