A simple, web-based repository for the management, access and analysis of micrographic images
Autor: | Danyon Harkins, Josephine Bowles, Michael Piper, Raul Ayala Davila, James Fraser, Laura Currey |
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Rok vydání: | 2019 |
Předmět: |
0301 basic medicine
Histology Physiology Computer science ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION Structured illumination microscopy Information Storage and Retrieval Lattice light-sheet microscopy computer.software_genre Rendering (computer graphics) 03 medical and health sciences Software Imaging Three-Dimensional Microscopy Web application Internet Microscopy Confocal 030102 biochemistry & molecular biology Multimedia business.industry Information Dissemination Computational Biology Reproducibility of Results Cell Biology General Medicine Tissue morphology 030104 developmental biology Central repository business computer |
Zdroj: | Journal of molecular histology. 50(6) |
ISSN: | 1567-2387 |
Popis: | Microscopy is advancing at a rapid pace, enabling high-speed, high-resolution analyses to be conducted in a wide range of cellular contexts. For example, the capacity to quickly capture high-resolution images from multiple optical sections over multiple channels with confocal microscopy has allowed researchers to gain deeper understanding of tissue morphology via techniques such as three-dimensional rendering, as have more recent advances such as lattice light sheet microscopy and superresolution structured illumination microscopy. With this, though, comes the challenge of storing, curating, analysing and sharing data. While there are ways in which this has been attempted previously, few approaches have provided a central repository in which all of these different aspects of microscopy can be seamlessly integrated. Here, we describe a web-based storage and analysis platform called Microndata, that enables relatively straightforward storage, annotation, tracking, analysis and multi-user access to micrographs. This easy to use tool will simplify and harmonise laboratory work flows, and, importantly, will provide a central storage repository that is readily accessed, even after the researcher responsible for capturing the images has left the laboratory. Microndata is open-source software, available at http://www.microndata.net/. |
Databáze: | OpenAIRE |
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