Angiogenic tumor markers, antiangiogenic agents and radiation therapy
| Autor: | Kevin Camphausen, Linda W. Chan |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Combination therapy
Angiogenesis medicine.medical_treatment Angiogenesis Inhibitors Pharmacology chemistry.chemical_compound Antiangiogenic agents Neoplasms Biomarkers Tumor Medicine Cytotoxic T cell Animals Humans Pharmacology (medical) Tumor marker Clinical Trials as Topic business.industry Cancer medicine.disease Vascular endothelial growth factor Radiation therapy Oncology chemistry Cancer research Angiogenesis Inducing Agents business |
| Zdroj: | Expert review of anticancer therapy. 3(3) |
| ISSN: | 1473-7140 |
| Popis: | There are many exciting avenues to pursue in angiogenesis-related cancer research. Until now, conventional therapy has targeted neoplastic cells within a tumor. However, tumor vasculature is emerging as a new cancer target. Antiangiogenic drugs are unique in having highly specific targets, while simultaneously carrying the potential to be effective against a wide breadth of cancer types. They also act synergistically with cytotoxic therapy. Currently, this combination of new antiangiogenic treatments with traditional cytotoxic treatments such as radiotherapy, may provide a powerful means of combating cancer. Strategic combination therapy, selecting for tumor type and angiogenic profile, may result in the realization of the promise and potential of antiangiogenic therapy. |
| Databáze: | OpenAIRE |
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