Physical activity and albuminuria were associated with painful diabetic polyneuropathy in type 2 diabetes in an ethnic Chinese population
| Autor: | Shih-Yi Lin, Wayne Huey-Herng Sheu, Sheng-Shu Chiang, Chia-Po Fu, Chia-Lin Lee, I-Te Lee, Jun-Sing Wang, Yuh-Min Song, Yu-Fen Li, Hsiu-Chen Liu |
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| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty China Diabetic neuropathy Clinical Biochemistry Population Taiwan Pain 030209 endocrinology & metabolism Type 2 diabetes Biochemistry 03 medical and health sciences 0302 clinical medicine Internal medicine Medicine Albuminuria Humans education PDPN Exercise Aged education.field_of_study business.industry Biochemistry (medical) Confounding Peripheral Nervous System Diseases Retrospective cohort study General Medicine Odds ratio Middle Aged medicine.disease Diabetes Mellitus Type 2 Female medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Clinica chimica acta; international journal of clinical chemistry. 462 |
| ISSN: | 1873-3492 |
| Popis: | Background Diabetic neuropathy is a common complication in patients with type 2 diabetes. However, the prevalence of painful diabetic polyneuropathy (PDPN) have been less studied. We examined the prevalence and risk factors of PDPN in outpatients with type 2 diabetes in an ethnic Chinese population. Methods This retrospective study enrolled 2358 outpatients with type 2 diabetes who had completed the Douleur Neuropathique en 4 Questions (DN4) questionnaire from January 2013 to October 2013. Patients with a total score ≥ 4 were defined as having PDPN. Results In all, 179 patients were diagnosed as having PDPN with a score of 4.49 on the DN4 questionnaire, compared with 0.66 for patients without PDPN. After adjusting the possible confounding factors, the risk of painful neuropathy was increased in the group without physical activity (Odds ratio 3.38, 95% CI 1.54–9.79), and in the group with macroalbuminuria (Odds ratio 2.31, 95% CI 1.44–3.73). Besides, there was a joint effect of macroalbuminuria and no physical activity habit on PDPN risk. Conclusions The prevalence of PDPN was 7.6% among our outpatients with type 2 diabetes. Less physical activity and albuminuria, respectively, increased the risk of PDPN and had a joint effect. |
| Databáze: | OpenAIRE |
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