Indium-111 leukocyte scanning and fracture healing
| Autor: | Fonda J. Bondurant, Allison C. Scott, Leon P. Mead, Bruce D. Browner |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Leukocyte scan Fracture site Bone healing Osteotomy Scintigraphy medicine Leukocytes Animals Orthopedics and Sports Medicine New zealand white Radionuclide Imaging Wound Healing medicine.diagnostic_test business.industry Osteomyelitis Indium Radioisotopes General Medicine Staphylococcal Infections medicine.disease Surgery Tibial Fractures Rabbits Osteitis business |
| Zdroj: | Journal of orthopaedic trauma. 4(1) |
| ISSN: | 0890-5339 |
| Popis: | This study was undertaken to determine the specificity of indium-111 leukocyte scans for osteomyelitis when fractures are present. Midshaft tibial osteotomies were performed in 14 New Zealand white rabbits, seven of which were infected postoperatively with Staphylococcus aureus per Norden's protocol. All 14 rabbits were scanned following injection with 75 microCi of indium 111 at 72 h after osteotomy and at weekly intervals for 4 weeks. Before the rabbits were killed, the fracture sites were cultured to document the presence or absence of infection. The results of all infected osteotomy sites were positive, whereas no positive scans were found in the noninfected osteotomies. We concluded from this study that uncomplicated fracture healing does not result in a positive indium-111 leukocyte scan. |
| Databáze: | OpenAIRE |
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