Exercise performance of the survivors of hyaline membrane disease
| Autor: | Gregory P. Heldt, William H. Tooley, Malcolm B. McIlroy, Thomas N. Hansen |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Male
medicine.medical_specialty Hyaline Membrane Disease medicine.medical_treatment Dead space Physical Exertion Positive pressure Positive-Pressure Respiration Heart Rate Oxygen therapy Internal medicine medicine Humans Continuous positive airway pressure Child Skin Mechanical ventilation business.industry Respiration Light Exercise Infant Newborn Carbon Dioxide Surgery Oxygen tension Oxygen Child Preschool Pediatrics Perinatology and Child Health Breathing Cardiology Female Lung Volume Measurements business |
| Zdroj: | The Journal of Pediatrics. 96:995-999 |
| ISSN: | 0022-3476 |
| DOI: | 10.1016/s0022-3476(80)80624-x |
| Popis: | We measured the cardiopulmonary response of 62 school-aged survivors of hyaline membrane disease to the stress of submaximal steady-state exercise on a cycle ergometer. The children represented a 48% follow-up of infants with HMD who-survived in our hospital in the years 1968 to 1974. They had incidences of wheezing, pulmonary infections, and abnormal chest roentgenograms after discharge similar to those in groups reported by other investigators. The first group required only supplemental oxygen or continuous positive airway pressure; the second required oxygen and CPAP plus mechanical ventilation with intermittent positive pressure; and the third, half of whom had been treated with positive pressure, developed pulmonary air leaks. Children in all groups had normal heart rates and oxygen consumptions for their heights and work rates. Ventilation was normal in all but three subjects. These three patients had had air leaks and one had severe bronchopulmonary dysplasia, requiring 36 months of oxygen therapy; the other two were only 5 years of age. All three developed hypercarbia during moderate exercise. There was no difference in the tidal volumes, respiratory rates, dead space, or the distribution of ventilation between the three groups and the normal subjects. The alveolar-to-skin oxygen tension gradient decreased in all groups and the normal subjects during light exercise, implying that the match of ventilation to perfusion improved. Most survivors of HMD appear to have normal cardiopulmonary function by school age. |
| Databáze: | OpenAIRE |
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