Low-level laser therapy (670 nm) on viability of random skin flap in rats
| Autor: | José A. Zuanon, Rafael Malfará Habenschus, Carlos Benatti Neto, Benedito Galvão Benze, Renan Fangel, Nivaldo Antonio Parizotto, Ana Claudia Muniz Renno, Paulo Sérgio Bossini |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Male
medicine.medical_specialty Necrosis medicine.medical_treatment Plastic sheet Dermatologic Surgical Procedures Skin flap Dermatology Surgical Flaps Microcirculation Laser therapy medicine Animals Low-Level Light Therapy Low level laser therapy Skin Tissue Survival business.industry Suture Techniques Dose-Response Relationship Radiation Radiotherapy Dosage Rats Surgery Lasers Semiconductor medicine.symptom business |
| Zdroj: | Lasers in Medical Science. 24:209-213 |
| ISSN: | 1435-604X 0268-8921 |
| DOI: | 10.1007/s10103-008-0551-5 |
| Popis: | This study investigated the effects of 670 nm laser, at different fluences, on the viability of skin flap in rats. One hundred male animals were used. The animals were divided into control group; group treated with 3 J/cm(2); group treated with 6 J/cm(2); group treated with 12 J/cm(2) and group treated with 24 J/cm(2). The skin flap was made on the backs of all animals studied, with a plastic sheet interposed between the flap and the donor site. Laser irradiation was done immediately after the surgery and on days 1, 2, 3 and 4 after surgery. The percentage of necrosis of the flap was calculated at the 7th postoperative day. Additionally, a sample of each flap was collected to enable us to count the blood vessels. Treated animals showed a statistically significant smaller area of necrosis than did the control group. The necrosis in the treated groups was 41.82% (group 2), 36.51% (group 3), 29.45% (group 4) and 20.37% (group 5). We also demonstrated that laser irradiation at 670 nm, at all doses used, had a stimulatory effect on angiogenesis. Our study showed that the 670 nm laser was efficient to increase the viability of the skin flap, at all fluences used, with a tendency of reaching better results at higher doses. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink