Immunoglobulin E in aqueous humour

Autor: P.L. Masson, C.G.M. Magnusson, J.P. Dernouchamps, J. Michiels
Rok vydání: 1985
Předmět:
Zdroj: Experimental Eye Research. 40:321-325
ISSN: 0014-4835
DOI: 10.1016/0014-4835(85)90016-8
Popis: The level of immunoglobulin E (IgE) was determined in the aqueous humour (AH) and serum by particle counting immunoassay (limit of sensitivity: 0·2 IU ml −1 ). This level in the AH was below 0·75 IU ml −1 in case of senile cataract ( n = 22) and ranged from this assumed normal value to 550 IU ml −1 in case of uveitis ( n = 37), Fuchs' cyclitis ( n = 11), intraocular tumour ( n = 7) and perforating ocular injury ( n = 6). To know whether the IgE increase was related to a possible local production the AH/serum concentration ratio for IgE was calculated and divided by that for albumin. Values higher than 0·60 were considered as suggestive of a local synthesis and were observed in 31 of the 37 samples examined.
Databáze: OpenAIRE