The KCC3 cotransporter as a therapeutic target for peripheral neuropathy
| Autor: | Kristopher T. Kahle, Eric Delpire |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Clinical Biochemistry Mice 03 medical and health sciences 0302 clinical medicine Drug Discovery medicine Animals Humans Pharmacology Symporters Chemistry Cell swelling Peripheral Nervous System Diseases medicine.disease Spinal cord Cell biology 030104 developmental biology Peripheral neuropathy medicine.anatomical_structure Symporter Molecular Medicine Cotransporter 030217 neurology & neurosurgery KCl cotransporter Bumetanide medicine.drug |
| Zdroj: | Expert Opinion on Therapeutic Targets. 21:113-116 |
| ISSN: | 1744-7631 1472-8222 |
| Popis: | The SLC12A family of K-Cl cotransporters mediates the tightly coupled and electroneutral movement of K+ and Cl- across plasma membranes. In the brain and spinal cord, KCC2 (SLC12A5) plays a key rol... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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