Arteries from human beings are less infectible by Staphylococcus aureus than polytetrafluoroethylene in an aortic dog model
Autor: | Olivier Goëau-Brissonnière, Edouard Kieffer, Marie-Hélène Nicolas, François Bacourt, Fabien Koskas |
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Rok vydání: | 1996 |
Předmět: |
medicine.medical_specialty
medicine.medical_treatment medicine.disease_cause Revascularization Prosthesis Dogs In vivo Cadaver Animals Humans Transplantation Homologous Medicine Vascular Diseases Derivation Polytetrafluoroethylene business.industry Arteries Staphylococcal Infections medicine.disease Blood Vessel Prosthesis Surgery Disease Models Animal surgical procedures operative medicine.anatomical_structure Staphylococcus aureus Bacteremia Circulatory system Female business Cardiology and Cardiovascular Medicine Artery |
Zdroj: | Journal of Vascular Surgery. 23(3):472-476 |
ISSN: | 0741-5214 |
DOI: | 10.1016/s0741-5214(96)80013-9 |
Popis: | Purpose: Treatment of aortoiliac prosthetic graft infections includes the removal of the infected material and repeat revascularization if necessary. The risk of infection of the graft material used for the repeat revascularization has been the drawback of its use in situ except with autografts. Good results were obtained in this setting by use of in situ arterial allografts. The purpose of our study was to compare in vivo the infectibility of arteries used as allografts to the infectibility of commercially available prostheses.Methods: Twelve dogs underwent thoracoabdominal aortic bypass with use of either an artery from a human being (n=6) or an expanded polytetrafluoroethylene (ePTFE) graft (n=6). One month later, bacteremia was produced with Staphylococcus aureus. One week after bacterial challenge, the animals were killed to recover the grafts. Each graft then underwent bacterial study.Results: None of the arterial grafts grew bacteria, whereas four of the six ePTFE grafts (P |
Databáze: | OpenAIRE |
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