Duodeno-pancreatic neuroendocrine tumours
| Autor: | George Konstantoudakis, Konstantina Petropoulou, George Giannopoulos, George Peros, George H. Sakorafas, Aikaterini Parasi |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Biopsy Glucagonoma Neuroendocrine tumors Gastroenterology Duodenal Neoplasms Internal medicine medicine Biomarkers Tumor Humans Multiple endocrine neoplasia Insulinoma VIPoma Aged business.industry General surgery Somatostatinoma Middle Aged medicine.disease Immunohistochemistry Neoplasm Proteins Pancreatic Neoplasms Neuroendocrine Tumors medicine.anatomical_structure Treatment Outcome Oncology Pancreatectomy Female Pancreas business |
| Zdroj: | European journal of cancer care. 19(3) |
| ISSN: | 1365-2354 |
| Popis: | PEROS G., SAKORAFAS G.H., KONSTANTOUDAKIS G., GIANNOPOULOS G.A., PETROPOULOU K. & PARASI A. (2010) European Journal of Cancer Care 19, 393–402 Duodeno-pancreatic neuroendocrine Tumours Duodeno-pancreatic neuroendocrine tumours (DP-ETs) are increasingly diagnosed today due to the widespread use of modern imaging methods. Duodeno-pancreatic endocrine tumours should be treated by radical surgical resection, which offers a high chance for cure when the disease is localized. A high index of suspicion is required in these patients for the presence of a multiple endocrine neoplasia type syndrome. We present four patients with DP-ET surgically treated at our department between 2000 and 2004. Histological/immunohistochemical diagnosis was somatostatin-producing tumour in the first patient, oncocytic endocrine tumour positive for neurone-specific enolase and focally for chromogranin in the second patient, glucagonoma and pancreatic polypeptide-producing endocrine pancreatic tumour in the third patient, and gastrin, somatostatin, calcitonin, insulin and adrenocorticotropic hormone (ACTH)-producing tumour in the fourth. The second patient died 6.5 years following surgery due to disseminated disease. |
| Databáze: | OpenAIRE |
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