Multiple Microcarcinoids Arising in Chronic Ulcerative Colitis
| Autor: | Bruce Mcneely, David A. Owen, Michael E. Pezim |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Male
Pathology medicine.medical_specialty Carcinoid Tumor Adenocarcinoma Inflammatory bowel disease Gastroenterology Neoplasms Multiple Primary Gross examination Internal medicine Intestinal Neoplasms medicine Humans Colitis pernicious anemia business.industry Stomach General Medicine Middle Aged Hyperplasia medicine.disease Ulcerative colitis digestive system diseases medicine.anatomical_structure Dysplasia Colitis Ulcerative business |
| Zdroj: | American Journal of Clinical Pathology. 98:112-116 |
| ISSN: | 1943-7722 0002-9173 |
| DOI: | 10.1093/ajcp/98.1.112 |
| Popis: | A 50-year-old man who had chronic ulcerative colitis with dysplasia and two synchronous carcinomas had a total colectomy. Microscopic examination of the resected specimen revealed multiple microcarcinoids that were all smaller than 2 mm in diameter and not visible with gross examination. Histologic examination revealed that they were similar to microcarcinoids of the stomach encountered in patients with pernicious anemia. In this patient, however, there was no associated endocrine cell hyperplasia in the overlying mucosa, and the carcinoids may have arisen from dysplastic stem cells in the colonic crypts. |
| Databáze: | OpenAIRE |
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