Impact of therapeutic and high doses of florfenicol on kidney and liver functional indicators in goat
| Autor: | Zohaib Ahmed Bhutto, Jan Muhammad Shah, Muhammad Asif Arain, Tahmina Shah, Qurban Ali Shah, Muhammad Saeed, Toufique Ahmed Qureshi, Farman Ali Siyal |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Florfenicol medicine.medical_specialty florfenicol 040301 veterinary sciences Bilirubin Veterinary medicine Biology Pharmacology blood chemistry SF1-1100 Transaminase 0403 veterinary science 03 medical and health sciences chemistry.chemical_compound Internal medicine SF600-1100 medicine therapeutic and high doses Creatinine Kidney General Veterinary goat 04 agricultural and veterinary sciences Animal culture 030104 developmental biology Endocrinology medicine.anatomical_structure chemistry Blood chemistry liver and kidney function tests Urea Alkaline phosphatase Research Article |
| Zdroj: | Veterinary World, Vol 9, Iss 10, Pp 1135-1140 (2016) Veterinary World |
| ISSN: | 2231-0916 0972-8988 |
| Popis: | Aim: The aim of this study was to evaluate the impact of therapeutic and high doses of florfenicol on kidney and liver functional indicators in goat species. Materials and Methods: Six mature, healthy goats (combine breed and sex) with average weight 25 kg were selected for this study. The therapeutic (20 mg/kg b.w.) and high doses (40 and 60 mg) of florfenicol were administered for 3 days with 24 h interval. Blood samples were collected at 0, 24, 48, 72, 96, and 120 h following the each administered dose. Results: The results showed that the therapeutic dose of florfenicol produced nonsignificant effect on serum urea, creatinine, total protein (TP), alkaline phosphatase (ALP), gamma-glutamyl transferase (GGT) and bilirubin on all timings, and increased (p |
| Databáze: | OpenAIRE |
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