Humoral immune response of dogs after vaccination against leptospirosis measured by an IgM- and IgG-specific ELISA
| Autor: | E.G. Hartman, J.A. van der Donk, M. van Houten, J.F. Frik |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1984 |
| Předmět: |
Serotype
Booster vaccination Male Diergeneeskunde Immunology Enzyme-Linked Immunosorbent Assay complex mixtures Immune system Dogs medicine Animals Leptospirosis Dog Diseases General Veterinary biology Vaccination Primary response medicine.disease biology.organism_classification Virology Antibodies Bacterial Immunoglobulin M Immunoglobulin G biology.protein Female Antibody Leptospira interrogans |
| Zdroj: | Veterinary Immunology and Immunopathology, 7(3-4), 245. Elsevier |
| ISSN: | 0165-2427 |
| Popis: | An IgM- and IgG-specific ELISA was used to measure the antibody response stimulated in dogs by vaccination with a leptospiral bacterin containing chemically inactivated Leptospira interrogans serotype icterohaemorrhagiae and serotype canicola leptospires. All dogs produced anti-leptospiral IgM and IgG. The IgM production was of the primary response type after each vaccination (primary vaccination, booster vaccination and annual revaccination). A substantial anti-leptospiral IgG response could be demonstrated only after the first booster vaccination and the annual revaccination. Annual revaccination resulted in a higher and much longer persisting IgG response than did the first booster vaccination. A revision of the vaccination scheme is suggested. |
| Databáze: | OpenAIRE |
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