Randomized comparison between 2-link cell design biolimus A9-eluting stent and 3-link cell design everolimus-eluting stent in patients with de novo true coronary bifurcation lesions: the BEGIN trial

Autor: Harumi Katoh, Yoshihisa Shimada, Koichi Kishi, Yoshihiro Morino, Kiyoshi Hibi, Yasuhiro Morita, Masahiro Yamawaki, Mikihito Toda, Yutaka Hikichi, Kazuya Kawai, Toshiya Muramatsu, Shigenori Ito, Kazuaki Mitsudo, Yuji Ikari, Kazuhiro Ashida, Yoritaka Otsuka, Takashi Fujii, Shingo Hosogi, Jiro Ando, Kazushige Kadota, Yoshisato Shibata, Hiroshi Ohira, Yasushi Fuku, Yasuhiro Tarutani, Yoshihisa Kinoshita, Yoshiaki Ito, Yuichi Noguchi
Rok vydání: 2018
Předmět:
Zdroj: Heart and vessels. 34(8)
ISSN: 1615-2573
Popis: The appropriate stent platform for treating coronary bifurcation lesions (CBLs) remains controversial. Previous bench tests have demonstrated the superiority of a 2-link cell design to 3-link cell design for creating inter-strut dilation at the side branch ostium. This randomized multicenter prospective BEGIN trial compared the biodegradable polymer-based biolimus A9-eluting stent (2-link BES) with the durable polymer-based cobalt chromium everolimus-eluting stent (3-link EES) in 226 patients with de novo CBLs. Patients with true bifurcations, defined as > 50% stenosis in the main vessel and side branch (SB) and an SB diameter > 2.25 mm, were enrolled. Guide wire re-crossing to the distal cell (near the carina) in the jailed SB and final kissing inflation were recommended. The SB angiographic endpoint was
Databáze: OpenAIRE