Outcome of intrahepatic portosystemic shunt diagnosed prenatally
Autor: | Bernard Benoit, Corinne Boyer, Bérengère Francois, Frédéric Gottrand, Alain Lachaux, Stéphanie De Smet |
---|---|
Rok vydání: | 2017 |
Předmět: |
Male
medicine.medical_specialty Vascular Malformations Population Prenatal diagnosis Ultrasonography Prenatal 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Internal medicine medicine Humans Child education Retrospective Studies education.field_of_study Portal Vein business.industry Infant Newborn Focal nodular hyperplasia Infant Retrospective cohort study Hepatology Prognosis medicine.disease Surgery Shunt (medical) Child Preschool Pediatrics Perinatology and Child Health Gestation Female 030211 gastroenterology & hepatology Radiology Portosystemic shunt business Follow-Up Studies |
Zdroj: | European Journal of Pediatrics. 176:1613-1618 |
ISSN: | 1432-1076 0340-6199 |
Popis: | We analyzed the characteristics of the population with congenital portosystemic shunt diagnosed during the antenatal period and the organization of their perinatal care. This multicentric retrospective study included all the patients with a prenatal diagnosis of congenital portosystemic shunt. Between 1999 and 2015, 12 patients were included. Prenatal diagnosis was done at a median 26.5 weeks of gestation (21-34). All the patients presented intrahepatic CPSS, three of them had associated congenital cardiopathy, and one a Bannayan-Zonana syndrome. Ten patients had simple outcome on conservative treatment, eight of them having a spontaneous closure of their portosystemic shunt within the first 2 years of life. One patient had surgical treatment which failed and he developed a focal nodular hyperplasia. Another patient had radiological interventional closure of his shunt which was complicated by a venal portal thrombosis.Outcome of intrahepatic portosystemic shunt diagnosed prenatally is good in the majority of cases. What is known: • Multiples studies exist on congenital porto systemic shunt but when the diagnosis is done after birth. • The evolution, management, and complication are well known. What is new: • There is very few studies with only patients diagnosed in antenatal and it is a large series of cases. • Outcome of intrahepatic portosystemic shunt diagnosed prenatally is good in the majority of cases. |
Databáze: | OpenAIRE |
Externí odkaz: |