Prevalence of chronic obstructive pulmonary disease in patients with rheumatoid arthritis: A cross‐sectional study
Autor: | Sung Jae Choi, Gwan Gyu Song, Cho Hee Bang, Ji Hyun Lim, Hongdeok Seok, Jae Hyun Jung |
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Rok vydání: | 2021 |
Předmět: |
Adult
Male Spirometry medicine.medical_specialty National Health and Nutrition Examination Survey Cross-sectional study Logistic regression Arthritis Rheumatoid Pulmonary Disease Chronic Obstructive 03 medical and health sciences 0302 clinical medicine Rheumatology Internal medicine Republic of Korea Prevalence medicine Humans 030212 general & internal medicine Aged 030203 arthritis & rheumatology COPD medicine.diagnostic_test business.industry Smoking Confounding Odds ratio Middle Aged Nutrition Surveys medicine.disease respiratory tract diseases Cross-Sectional Studies Rheumatoid arthritis Female business |
Zdroj: | International Journal of Rheumatic Diseases. 24:774-780 |
ISSN: | 1756-185X 1756-1841 |
DOI: | 10.1111/1756-185x.14129 |
Popis: | Objective Rheumatoid arthritis (RA) and chronic obstructive pulmonary disease (COPD) are both chronic inflammatory diseases; the prevalence of COPD in RA patients is known to be high. However, the prevalence of both RA and COPD differs according to sex; the relationship between RA and COPD may also vary according to sex. Therefore, we investigated the prevalence of COPD and its association in patients with RA in Korea by sex. Methods We conducted a nationwide cross-sectional study using data from the Korea National Health and Nutrition Examination Survey. A total of 12 417 men and 15 878 women were included. In this study, RA was defined as physician diagnosed or currently under RA treatment. COPD was defined based on spirometry results, chronic symptoms, and smoking history. Multivariable logistic regression models were employed and we calculated the odds ratios (ORs) and 95% confidence intervals (CIs) for COPD prevalence in patients with RA. Results The prevalence of COPD was 15.5% in men with RA, 3.5% in women with RA, 7.8% in men without RA, and 2.2% in women without RA. After adjustment for potential confounding variables, including smoking status, RA was significantly associated with COPD in men (OR 2.16, 95% CI 1.06-4.40), but not in women (OR 1.58, 95% CI 0.81-3.10). Conclusions In Korea, the prevalence of COPD was high in patients with RA of both sexes; RA and COPD was significantly likely to be associated in men, but not in women. |
Databáze: | OpenAIRE |
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