Candiduria among HIV- Infected Patients Attending a Tertiary Hospital in Benin City
| Autor: | NO Esebelahie, FO Newton-Esebelahie, R Omoregie, I. B. Enweani |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Gynecology
Voriconazole education.field_of_study Pediatrics medicine.medical_specialty business.industry General Chemical Engineering Population medicine.disease Corpus albicans medicine Hiv infected patients Population study Benin city Systemic candidiasis education business Fluconazole medicine.drug |
| Zdroj: | African Journal of Clinical and Experimental Microbiology; Vol 15, No 2 (2014); 84-90 |
| ISSN: | 1595-689X |
| Popis: | Background : Candiduria is a common finding. However, in immunocompromised patients like HIV-infected individuals, it has high risk of morbidity and mortality as it could be a pointer to systemic candidiasis. Unfortunately, there are no clear criteria for differentiating between colonization and infection or between upper or lower urinary tract infections. Objective : This study focused on determining the spectrum of Candida species implicated in candiduria among HIV-infected individuals and their susceptibility to fluconazole and voriconazole in a tertiary hospital. Methods : A total of 300 subjects comprising of 200 HIV patients and 100 non-HIV individuals were used for this study. Clean catch midstream were collected from each individual and processed using standard microbiological techniques. Emergent Candida isolates were identified with CHROMagar Candida and sugar fermentation tests. Results : The overall prevalence of candiduria among HIV patients was 13.5%. HAART-naive patients had a significantly higher prevalence (OR=4.165, 95%CI=1.602, 10.828; P=0.0038) than their counterpart on highly active antiretroviral therapy (HAART). Female gender was a significant risk factor for acquiring candiduria. Age had no significant effect on the prevalence of candiduria in this study. A CD4+ count |
| Databáze: | OpenAIRE |
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