Supplementary Figure 6 from PDLIM2 Is a Marker of Adhesion and β-Catenin Activity in Triple-Negative Breast Cancer

Autor: Rosemary O'Connor, Alexander Marx, Suet-Feung Chin, Carlos Caldas, René Bernards, Richard D. Kennedy, William M. Gallagher, Ciara H. O'Flanagan, Nollaig Healy, Milan Bustamante-Garrido, Niamh E. Buckley, Bruce Moran, Bo Li, Katja Simon-Keller, Shelley J. Edmunds, Orla T. Cox
Rok vydání: 2023
Popis: Related to Figure 6: Western blots and immunofluorescence images of PDLIM2 and b-catenin phospho-Ser675 expression and localization in BT549 cells overexpressing HA-PDLIM2 are included. Graph depicting measurements of cell migration in HA-PDLIM2-expressing BT549 is shown. The effects of suppression of PDLIM2 on b-catenin and b1-integrin levels in HCC1806 and MDA-MB-231-LUC2 are shown. Further analyses of effects of loss of adhesion and also, serum starvation, on PDLIM2 and active b-catenin subcellular localization in TN Breast cell lines are also shown.
Databáze: OpenAIRE