Cost-Utility of Bilateral Versus Unilateral Cochlear Implantation in Adults: A Randomized Controlled Trial
| Autor: | Wendy J. Huinck, Yvette E. Smulders, Inge Stegeman, Wilko Grolman, Albert B. Rinia, Rolien Free, Gijsbert A. van Zanten, Vedat Topsakal, Emmanuel A. M. Mylanus, Robert J. Stokroos, Bert Maat, Alice van Zon, Johan H. M. Frijns |
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| Přispěvatelé: | Surgical clinical sciences, Ear, nose & throat, RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience, MUMC+: MA Keel Neus Oorheelkunde (9), KNO, Perceptual and Cognitive Neuroscience (PCN) |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Male
Pediatrics Cost effectiveness medicine.medical_treatment Cost-Benefit Analysis health status Deafness Sensory disorders Donders Center for Medical Neuroscience [Radboudumc 12] Functional Laterality law.invention surgery Indirect costs 0302 clinical medicine Randomized controlled trial law Cochlear implant Young adult 030223 otorhinolaryngology Non-U.S. Gov't PERSPECTIVE Cost-utility Research Support Non-U.S. Gov't Age Factors Middle Aged Cochlear Implantation Sensory Systems STATE Multicenter Study Treatment Outcome Randomized Controlled Trial young adult Female Quality-Adjusted Life Years medicine.symptom Adult medicine.medical_specialty Adolescent Hearing loss Research Support 03 medical and health sciences Deafness/economics medicine Journal Article health care costs Humans Comparative Study Cochlear Implants/economics Aged Bilateral cochlear implantation business.industry Cochlear Implantation/economics Surgery Quality-adjusted life year LIFE Cochlear Implants Otorhinolaryngology life expectancy Cost-effectiveness Neurology (clinical) Implant business 030217 neurology & neurosurgery |
| Zdroj: | Otology and Neurotology, 37(1), 38-45 Otology & Neurotology, 37, 38-45 Otology & Neurotology, 37(1), 38. Lippincott Williams and Wilkins Otology & Neurotology, 37, 1, pp. 38-45 Otology & Neurotology, 37(1), 38-45. LIPPINCOTT WILLIAMS & WILKINS |
| ISSN: | 1531-7129 |
| Popis: | Item does not contain fulltext OBJECTIVE: To study the cost-utility of simultaneous bilateral cochlear implantation (CI) versus unilateral CI. STUDY DESIGN: Randomized controlled trial (RCT). SETTING: Five tertiary referral centers. PATIENTS: Thirty-eight postlingually deafened adults eligible for cochlear implantation. INTERVENTIONS: A cost-utility analysis was performed from a health insurance perspective. MAIN OUTCOME MEASURES: Utility was assessed using the HUI3, TTO, VAS on hearing, VAS on general health and EQ-5D. We modeled the incremental cost per quality-adjusted life year (QALY) of unilateral versus bilateral CI over periods of 2, 5, 10, 25 years, and actual life-expectancy. RESULTS: Direct costs for unilateral and bilateral CI were euro43,883 +/- euro11,513(SD) and euro87,765 +/- euro23,027(SD) respectively. Annual costs from the second year onward were euro3,435 +/- euro1,085(SD) and euro6,871 +/- euro2,169(SD), respectively. A cost-utility analysis revealed that a second implant became cost-effective after a 5- to 10-year period, based on the HUI3, TTO, and VAS on hearing. CONCLUSION: This is the first study that describes a cost-utility analysis to compare unilateral with simultaneous bilateral CI in postlingually deafened adults, using a multicenter RCT. Compared with accepted societal willingness-to-pay thresholds, simultaneous bilateral CI is a cost-effective treatment for patients with a life expectancy of 5-10 years or longer. |
| Databáze: | OpenAIRE |
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