First experience in clinical application of hyperspectral endoscopy for evaluation of colonic polyps
| Autor: | Sarah Diamond, Vassiliki L. Tsikitis, Charlie Borzy, Kyla Siemens, Sarah E. Bohndiek, James Joseph, Jonghee Yoon, Dale J. Waterhouse |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Endoscope Colorectal cancer Colonic Polyps General Physics and Astronomy Early detection Colonoscopy General Biochemistry Genetics and Molecular Biology Adenomatous Polyps medicine Humans General Materials Science Spectral data neoplasms Early Detection of Cancer medicine.diagnostic_test Crc screening business.industry General Engineering Hyperspectral imaging General Chemistry medicine.disease digestive system diseases Endoscopy Radiology Colorectal Neoplasms business |
| Zdroj: | Journal of Biophotonics. 14 |
| ISSN: | 1864-0648 1864-063X |
| Popis: | Early detection and resection of adenomatous polyps prevents their progression to colorectal cancer (CRC), significantly improving patient outcomes. Polyps are typically identified and removed during white-light colonoscopy. Unfortunately, the rate of interval cancers that arise between CRC screening events remains high, linked to poor visualization of polyps during screening and incomplete polyp removal. Here, we sought to evaluate the potential of a hyperspectral endoscope (HySE) to enhance polyp discrimination for detection and resection. We designed, built and tested a new compact HySE in a proof-of-concept clinical study. We successfully collected spectra from three tissue types in seven patients undergoing routine colonoscopy screening. The acquired spectral data from normal tissue and polyps, both pre- and post- resection, were subjected to quantitative analysis using spectral angle mapping and machine learning, which discriminated the data by tissue type, meriting further investigation of HySE as a clinical tool. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text