Evolution of Malignant Lymphoma in Agnogenic Myeloid Metaplasia
| Autor: | Juri Kopolovic, Chaim Hershko, Amos M. Yinnon, Leah Dollberg |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Adult
Male Oncology Cancer Research medicine.medical_specialty Pathology Lymphoma business.industry General Medicine medicine.disease Hematopoiesis Malignant lymphoma Primary Myelofibrosis hemic and lymphatic diseases Internal medicine medicine Humans Agnogenic myeloid metaplasia Myelofibrosis business |
| Zdroj: | Oncology. 45:373-377 |
| ISSN: | 1423-0232 0030-2414 |
| DOI: | 10.1159/000226644 |
| Popis: | Two young arab patients are described in whom malignant lymphoma developed within less than 1 year of the diagnosis of agnogenic myeloid metaplasia. Both patients showed a satisfactory response to combined chemotherapy. One of them died of hepatitis B at 10 months and the other is alive and in clinical remission 25 months after initial diagnosis. These observations demonstrate the close relation between myeloproliferative and lymphoproliferative syndromes and illustrate the diversity of malignant lymphoproliferative disorders into which agnogenic myeloid metaplasia may evolve in the course of disease. Our experience also demonstrates the ease with which some patients with an 'end stage' myeloproliferative disorder may respond to standard chemotherapy designed for the treatment of malignant lymphoma. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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