Effects of stock differences in the acceleration of puberty in female mice
| Autor: | R. Pewtress, S. McDonald, J. J. Cowley |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Embryology
medicine.medical_specialty Physiology Robertsonian translocation Chromosomal translocation Mice Inbred Strains Urine Biology Body weight medicine.disease_cause Translocation Genetic Mice Endocrinology Estrus Internal medicine medicine Sexual maturity Animals Sexual Maturation Estrous cycle Body Weight Obstetrics and Gynecology Cell Biology Reproductive Medicine Female Faecal pellet |
| Zdroj: | Journal of reproduction and fertility. 83(1) |
| ISSN: | 0022-4251 |
| Popis: | Newly born TO strain female mice were exposed daily to the urine from male albino mice of the same and CFLP strains, from feral mice carrying Robertsonian translocation chromosomes and to water as a control condition. At 21 days of age, when exposure was discontinued, there were differences in body weight between treatments which were not present when adult. Exposure to urine from mice with Robertsonian translocations did not accelerate puberty and the interval between vaginal opening and first oestrus was longer (4.2 days) than in mice exposed to the urine from the albino strains (1.8 days). Mice exposed to the urine from the Robertsonian stock were in dioestrus more often than those exposed to the urine from laboratory strains. The Robertsonian mice also differed in their behaviour in an open arena in that they passed fewer faecal pellets than those exposed to the urine from the albino mice. The water control mice defecated the least frequently. The mice exposed to the Robertsonian urine were less active than the laboratory strains but the differences did not reach an acceptable level (P less than 0.06) of significance. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|