Two new ent-abietane diterpenoids from Euphorbia helioscopia
| Autor: | Yao Zhang, Xing-Lin Xie, Wei Li, Zhao Yin, Jiao Yuan |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Pharmacology
biology Traditional medicine 010405 organic chemistry Organic Chemistry Euphorbiaceae Pharmaceutical Science General Medicine biology.organism_classification 01 natural sciences 0104 chemical sciences Analytical Chemistry 010404 medicinal & biomolecular chemistry chemistry.chemical_compound Complementary and alternative medicine chemistry Drug Discovery Molecular Medicine Euphorbia helioscopia Abietane |
| Zdroj: | Journal of Asian Natural Products Research. 22:632-638 |
| ISSN: | 1477-2213 1028-6020 |
| Popis: | Two new ent-abietane diterpenoids, euphcopenoids A (1) and B (2), along with six known analogues (3 – 8), were isolated from the whole plants of Euphorbia helioscopia. Their structures were determined by various spectroscopic methods (MS, UV, IR, and NMR), and the absolute configurations of compounds 1 and 2 were determined by quantum chemical ECD calculations. All compounds were screened for the cytotoxicity against A549 and HEPG2 cancer cell lines, but were inactive. |
| Databáze: | OpenAIRE |
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