Changes in exercise tolerance and resting haemodynamics during long-term treatment of heart failure with xamoterol
| Autor: | J. P. Boundhoure, H. M. Snow, L. Courtault, J. G. Kayanakis, J. M. Fauvel |
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| Rok vydání: | 1990 |
| Předmět: |
Male
medicine.medical_specialty Long term treatment Xamoterol Physical Exertion Cardiac index Cardiac Output Low Hemodynamics Propanolamines chemistry.chemical_compound Internal medicine Heart rate medicine Humans Multicenter Studies as Topic Pulmonary wedge pressure Exercise duration Aged business.industry Middle Aged medicine.disease chemistry Heart failure Anesthesia Cardiology Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | European heart journal. 11 |
| ISSN: | 0195-668X |
| Popis: | The long-term efficacy of xamoterol in improving effort capacity and haemodynamics was investigated in a study lasting 1 year in heart failure patients. Following a 3 month, double-blind period of treatment with xamoterol, patients continued therapy for a further 9 months. Exercise duration rose by 27% at 3 months and this improvement was maintained at 12 months. Similarly, the statistically significant increase in cardiac index and reduction in pulmonary wedge pressure and exercise heart rate persisted for 12 months. |
| Databáze: | OpenAIRE |
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