| Autor: |
Xiang Wei, Qin Chen, Lingtong Bu, Xi Wan, Zixian Jiao, Zixiang Han, Duohong Zou, Jisi Zheng, Chi Yang |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
ACS nano. 16(9) |
| ISSN: |
1936-086X |
| Popis: |
Total joint replacement (TJR) is widely applied as a promising treatment for the reconstruction of serious joint diseases but is usually characterized by critical loss of skeletal muscle attachment to metal joint prostheses, resulting in fibrous scar tissue formation and subsequent motor dysfunction. Tissue engineering technology may provide a potential strategy for skeletal muscle regeneration into metal joint prostheses. Here, a porous titanium (Ti) alloy scaffold coated with carbon nanotubes (CNTs) and mesoporous silica nanoparticles (MSNs) through electrophoretic deposition (EPD) was designed as a mechano-growth factor (MGF) carrier. This two-layered coating exhibits a nanostructured topology, excellent MGF loading, and prolonged release performance |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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