Toe-to-room temperature gradient correlates with tissue perfusion and predicts outcome in selected critically ill patients with severe infections
| Autor: | Jean-Luc Baudel, Jean-Rémi Lavillegrand, Bertrand Guidet, Guillaume Leblanc, Naïke Bigé, Pierre-Yves Boëlle, Jalel Tahiri, Safaa Nemlaghi, Claire Pichereau, Vincent Dubée, Gabriel Lejour, Simon Bourcier, Arnaud Galbois, Eric Maury, Hafid Ait-Oufella |
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| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Resuscitation Hemodynamics Critical Care and Intensive Care Medicine Microcirculation Sepsis 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Outcome medicine.diagnostic_test business.industry Septic shock Research Shock 030208 emergency & critical care medicine Temperature gradient medicine.disease Capillary refill Surgery 030228 respiratory system Shock (circulatory) Cardiology medicine.symptom business Perfusion |
| Zdroj: | Annals of Intensive Care |
| ISSN: | 2110-5820 |
| Popis: | Background Microcirculatory disorders leading to tissue hypoperfusion play a central role in the pathophysiology of organ failure in severe sepsis and septic shock. As microcirculatory disorders have been identified as strong predictive factors of unfavourable outcome, there is a need to develop accurate parameters at the bedside to evaluate tissue perfusion. We evaluated whether different body temperature gradients could relate to sepsis severity and could predict outcome in critically ill patients with severe sepsis and septic shock. Method We conducted a prospective observational study in a tertiary teaching hospital in France. During a 10-month period, all consecutive adult patients with severe sepsis or septic shock who required ICU admission were included. Six hours after initial resuscitation (H6), we recorded the hemodynamic parameters and four temperature gradients: central-to-toe, central-to-knee, toe-to-room and knee-to-room. Results We evaluated 40 patients with severe sepsis (40/103, 39 %) and 63 patients with septic shock (63/103, 61 %). In patients with septic shock, central-to-toe temperature gradient was significantly higher (12.5 [9.2; 13.8] vs 6.9 [3.4; 12.0] °C, P |
| Databáze: | OpenAIRE |
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