Hypothyroidism presenting as a polymyositis-like syndrome. Report of two cases
| Autor: | Barnes Hv, Frank C. Arnett, Corwin Q. Edwards, Koppes Gm, Marc C. Hochberg |
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| Rok vydání: | 1976 |
| Předmět: |
Adult
endocrine system medicine.medical_specialty Proximal muscle weakness endocrine system diseases Immunology Hormone replacement Electromyography Gastroenterology Polymyositis Diagnosis Differential Hypothyroidism Muscular Diseases Rheumatology Internal medicine Humans Immunology and Allergy Medicine Pharmacology (medical) Aspartate Aminotransferases Creatine Kinase L-Lactate Dehydrogenase Myositis biology medicine.diagnostic_test business.industry Thyroid Muscle weakness Alanine Transaminase Middle Aged medicine.disease medicine.anatomical_structure Endocrinology biology.protein Female Creatine kinase medicine.symptom Differential diagnosis business |
| Zdroj: | Arthritis & Rheumatism. 19:1363-1366 |
| ISSN: | 1529-0131 0004-3591 |
| DOI: | 10.1002/art.1780190621 |
| Popis: | Two patients with proximal muscle weakness and marked elevations of serum muscle enzymes were initially believed to have polymyositis; however electromyography and muscle biopsies were normal. Both patients were subsequently found to have hypothyroidism. Each regained her muscle strength, and serum enzymes normalized with thyroid hormone replacement. Because muscle weakness and an elevated creatine phosphokinase occur in most patients with hypothyroidism, thyroid dysfunction must be considered in the differential diagnosis of polymyositis. |
| Databáze: | OpenAIRE |
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