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Phylogeny of Frizzled receptors. Frizzled receptors from H. sapiens, D. melanogaster, the trematode S. mansoni [84], the planarian S. mediterranea [84], and the tapeworms E. multilocularis and H. microstoma [29] were aligned, and a phylogeny was estimated by Maximum Likelihood analysis (with a JTT model) using MEGA 5.2 [85]. The tree was rooted using the related Smoothened receptors. Bootstrap support values from 1,000 replicates are indicated next to the nodes. Nodes with lower than 50Â % support were collapsed. Genbank accession codes are given for H. sapiens and D. melanogaster; GeneDB accession codes are given for E. multilocularis and H. microstoma; gene names from [84] are given for S. mansoni and S. mediterranea. The fz4 genes of E. multilocularis and H. microstoma are indicated by arrows. (PDF 9 kb) |
