Regional Alterations in Long Bone 85Sr Clearance Produced by Internal Fixation Devices. Part II. Histomorphometry
| Autor: | David J. Simmons, Wayne J. Daum, Jason H. Calhoun |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Bone Screws Long bone Hemodynamics Osteotomy Bone and Bones Fracture Fixation Internal Dogs Postoperative Complications Ischemia medicine Animals Orthopedics and Sports Medicine Femur Wound Healing business.industry General Medicine Blood flow Anatomy medicine.disease Skeleton (computer programming) Osteopenia Bone Diseases Metabolic medicine.anatomical_structure Regional Blood Flow Orthopedic surgery Strontium Radioisotopes Surgery business Nuclear medicine Bone Plates |
| Zdroj: | Journal of Orthopaedic Trauma. 2:245-249 |
| ISSN: | 0890-5339 |
| DOI: | 10.1097/00005131-198802030-00012 |
| Popis: | The effects of each of the surgical stages involved in compression plating on the development of cortical thinning and porosity were assessed in the intact midshaft, stress-shielded femoral segments of adult mongrel dogs 6 months postoperatively. The data were evaluated in terms of a postsurgical tetracycline-based measure of remodeling and terminal /sup 85/Sr clearance (SrC) values for the plated segments of bone. Drilling had no effect on any parameter. Screw application was associated with minimal cortical thinning (p less than 0.05), while plate fixation clearly promoted thinning (p less than 0.01) and porosity (p less than 0.05). The percentage of labeled osteons, a measure of remodeling activity, increased only after plate fixation (p less than 0.05), and the labeling patterns suggested that most osteons had formed during the first 4 postsurgical months. That none of these changes were correlated with the 6-month SrC values suggests that the development of plate-induced osteopenia involves disparate histomorphometric time constants, rather than lack of any association. |
| Databáze: | OpenAIRE |
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