Powering up microbiome-microglia interactions

Autor:	John F. Cryan, Caoimhe M.K. Lynch, Gerard Clarke
Rok vydání:	2021
Předmět:	Intestine flora Microglia Physiology Microflora Microbiota Neurogenesis Cell Biology Biology Gastrointestinal Microbiome Metabolic pathway Immune system medicine.anatomical_structure medicine Nervous system development Microbiome Gastrointestinal microbiome Molecular Biology Neuroscience
Zdroj:	Cell Metabolism. 33:2097-2099
ISSN:	1550-4131
Popis:	Despite extensive evidence implicating the microbiota in regulating the immune system, the precise mechanisms underlying microbial control of microglial maturation remain unclear. In a methodological tour de force, Erny et al. (2021) identify acetate as an essential microbiota-derived molecule driving microglial metabolic pathways and functions during healthy and diseased states.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c5cdec5635a50adec767159164883c2 https://doi.org/10.1016/j.cmet.2021.10.006 Zobrazit plný text záznamu