Dose volume effects of re‐irradiation for locally recurrent nasopharyngeal carcinoma
| Autor: | Darren Mc Poon, Wai Tong Ng, J.C.H. Chow, Michael Ch Lee, Tin‐Ching Chau, Alice Kw Cheung, Chi-Leung Chiang, Jessica W.Y. Lai, Nelson Tc Fung, Edwin C.Y. Wong, Kwok-Hung Au, Anne W.M. Lee, Horace C.W. Choi, Victor Lee |
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| Rok vydání: | 2019 |
| Předmět: |
Re-Irradiation
medicine.medical_specialty Nasopharyngeal Carcinoma Equivalent dose business.industry Urology Nasopharyngeal Neoplasms Radiotherapy Dosage medicine.disease 030218 nuclear medicine & medical imaging Gross tumor volume 03 medical and health sciences 0302 clinical medicine Otorhinolaryngology Volume (thermodynamics) Nasopharyngeal carcinoma 030220 oncology & carcinogenesis medicine Humans Recurrent Nasopharyngeal Carcinoma Neoplasm Recurrence Local Complication business Small tumors |
| Zdroj: | Head & Neck. 42:180-187 |
| ISSN: | 1097-0347 1043-3074 |
| DOI: | 10.1002/hed.25988 |
| Popis: | BACKGROUND This study analyzed the dose volume effects of re-irradiation for locally recurrent nasopharyngeal carcinoma (NPC) and attempts to determine the optimal dose for the best survival. METHODS Ninety-one patients were studied. The local control, fatal complication, and overall survival were analyzed against the dose (in Equivalent Dose at 2 Gy/fractions) and recurrent gross tumor volume (GTV). RESULTS The local control and fatal complication rate appear to increase with prescribed dose. The overall survival peaks at around 60 Gy10 . Local control decreases significantly with increasing GTV (P |
| Databáze: | OpenAIRE |
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