Stress Response in Suicide Attempters with Borderline Personality Disorder: The Role of Behavioral Problems in Childhood

Autor:	Barbara Stanley, Beth S. Brodsky, Hanga Galfalvy, Ilana Gratch, John G. Keilp, Liat Itzhaky
Rok vydání:	2020
Předmět:	Adult Hypothalamo-Hypophyseal System Adolescent Hydrocortisone MEDLINE Suicide Attempted Behavioral Symptoms Article Fight-or-flight response Young Adult 03 medical and health sciences 0302 clinical medicine Borderline Personality Disorder Stress Physiological Humans Medicine Saliva Borderline personality disorder Suicide attempters business.industry Extramural Middle Aged medicine.disease 030227 psychiatry Psychiatry and Mental health Heterogeneous population business Stress Psychological 030217 neurology & neurosurgery Clinical psychology
Zdroj:	Psychiatry
ISSN:	1943-281X 0033-2747
Popis:	OBJECTIVE: Suicidal individuals are a heterogeneous population and may differ in systematic ways in their responsiveness to stress. The primary aim of the present study was to identify whether a different pattern of physiological stress response exists among adult suicide attempters with a history of behavioral problems during childhood and adolescence, which earlier studies have related to both decreased activity of the HPA axis and to suicidal behaviors. METHOD: Seventy-eight participants with Borderline Personality Disorder were assessed using the SCID-II, and completed self-report measures assessing their history of suicide attempts, history of aggressive behaviors, depressive symptoms, history of lifetime abuse and demographics. Participants’ cortisol reactivity was assessed using the Trier Social Stress Test. RESULTS: Analyses indicated that suicide attempters with a history of behavioral problems in youth (n=30) had a significantly lower response to stress than both suicide attempters without such a history (n=26) and non-attempters (n=22), when controlling for lifetime history of abuse. The groups did not differ in basal cortisol. CONCLUSIONS: These findings suggest a unique subtype of suicide attempter among those with Borderline Personality Disorder, characterized by a blunted physiological stress response.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c52e3a0505fd16a82ada7ee25cf53ca https://doi.org/10.1080/00332747.2020.1716439 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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