Is osteoporosis a predictor for future sarcopenia or vice versa? Four-year observations between the second and third ROAD study surveys
| Autor: | Noriko Yoshimura, Toru Akune, Sakae Tanaka, Hiroyuki Oka, Shigeyuki Muraki, Kozo Nakamura, R. Kodama, Toshiko Iidaka, Hiroshi Kawaguchi |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Sarcopenia medicine.medical_specialty Endocrinology Diabetes and Metabolism Osteoporosis 030209 endocrinology & metabolism 03 medical and health sciences Age Distribution 0302 clinical medicine Japan Bone Density Internal medicine Prevalence medicine Humans Cumulative incidence 030212 general & internal medicine Sex Distribution Aged Femoral neck Aged 80 and over business.industry Incidence Incidence (epidemiology) Odds ratio Middle Aged medicine.disease Health Surveys Rheumatology Confidence interval medicine.anatomical_structure Physical therapy Female business Follow-Up Studies |
| Zdroj: | Osteoporosis International. 28:189-199 |
| ISSN: | 1433-2965 0937-941X |
| Popis: | In a 4-year follow-up study that enrolled 1099 subjects aged ≥60 years, sarcopenia prevalence was estimated at 8.2%. Moreover, the presence of osteoporosis was significantly associated with short-term sarcopenia occurrence, but the reciprocal relationship was not observed, suggesting that osteoporosis would increase the risk of osteoporotic fracture and sarcopenia occurrence. The present 4-year follow-up study was performed to clarify the prevalence, incidence, and relationships between sarcopenia (SP) and osteoporosis (OP) in older Japanese men and women. We enrolled 1099 participants (aged, ≥60 years; 377 men) from the second survey of the Research on Osteoarthritis/Osteoporosis against Disability (ROAD) study (2008–2010) and followed them up for 4 years. Handgrip strength, gait speed, skeletal muscle mass, and bone mineral density were assessed. SP was defined according to the Asian Working Group for Sarcopenia. OP was defined based on the World Health Organization criteria. SP prevalence was 8.2% (men, 8.5%; women, 8.0%) in the second survey. In those with SP, 57.8% (21.9%; 77.6%) had OP at the lumbar spine L2–4 and/or femoral neck. SP cumulative incidence was 2.0%/year (2.2%/year; 1.9%/year). Multivariate regression analysis revealed that OP was significantly associated with SP occurrence within 4 years (odds ratio, 2.99; 95% confidence interval, 1.46–6.12; p |
| Databáze: | OpenAIRE |
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