Alkali-resistant hemoglobin in aplastic anemia of both acquired and congenital types
| Autor: | Park S. Gerald, Nasrollah T. Shahidi, Louis K. Diamond |
|---|---|
| Rok vydání: | 1962 |
| Předmět: |
medicine.medical_specialty
Anemia business.industry Thalassemia Anemia Aplastic General Medicine Alkalies medicine.disease Alkali-resistant hemoglobin Gastroenterology Hemoglobins hemic and lymphatic diseases Internal medicine Immunology Fetal hemoglobin medicine Humans Hemoglobin Aplastic anemia business Multiple myeloma pernicious anemia |
| Zdroj: | The New England journal of medicine. 266 |
| ISSN: | 0028-4793 |
| Popis: | DURING a study of patients with aplastic anemia1 it was noted that blood from such patients showed an increased amount of alkali-resistant hemoglobin. It is known that increased production of alkali-resistant or fetal hemoglobin is usually associated with some genetically determined anemias such as thalassemia and sickle-cell anemia. Scattered reports have also indicated that production of fetal hemoglobin may be reactivated in some acquired disorders such as pernicious anemia, multiple myeloma,2 molar pregnancy3 and aplastic anemia.2 , 4 , 5 The evaluation of alkali-resistant hemoglobin in this last condition, however, has yielded conflicting results. Although some investigators have found abnormal amounts of this hemoglobin . . . |
| Databáze: | OpenAIRE |
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