Immunohistological Observations on the Spleen B Lymphocyte Populations from Whole-body Irradiated Rats
| Autor: | Hervé Bazin, Bernadette Platteau |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
medicine.medical_specialty
Pathology Time Factors Lymphocyte Population Spleen Biology Ionizing radiation Leukocyte Count Internal medicine Follicular phase medicine Animals Irradiation Radiosensitivity education B-Lymphocytes education.field_of_study Dose-Response Relationship Radiation Rats Inbred Strains Organ Size General Medicine Marginal zone Rats Endocrinology medicine.anatomical_structure Cesium Radioisotopes Gamma Rays Female Whole-Body Irradiation |
| Zdroj: | International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine. 45:321-329 |
| ISSN: | 0020-7616 |
| Popis: | SummaryThe effects of a single exposure to caesium gamma rays administered to rats at high dose rate have been observed on their spleen B lymphocyte populations. These effects increase with the dose as well as with the time, at least within the following ranges of experimental conditions: from 0 to 12 Gy and observation times of 1 and 3 days after irradiation. Doses less than or equal to 1·50 Gy lead to only a slight reduction of the B lymphocyte populations. On the contrary, doses equal to or greater than 3·50 Gy are extremely destructive for the spleen B lymphocytes. The non-circulating B lymphocyte population of the marginal zone compartment seems more susceptible to ionizing radiations than the circulating B lymphocyte population of the follicular compartment. |
| Databáze: | OpenAIRE |
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