A novel phage display based platform for exosome diversity characterization

Autor:	Domenico Maisano, Selena Mimmi, Vincenzo Dattilo, Fabiola Marino, Massimo Gentile, Eleonora Vecchio, Giuseppe Fiume, Nancy Nisticò, Annamaria Aloisio, Maria Penelope de Santo, Giovanni Desiderio, Vincenzo Musolino, Saverio Nucera, Francesca Sbrana, Sebastiano Andò, Simone Ferrero, Andrea Morandi, Francesco Bertoni, Ileana Quinto, Enrico Iaccino
Rok vydání:	2022
Předmět:	Bacteriophages General Materials Science Exosomes Biomarkers
Zdroj:	Nanoscale. 14:2998-3003
ISSN:	2040-3372 2040-3364
Popis:	We present an innovative approach allowing the identification, isolation, and molecular characterization of disease-related exosomes based on their different antigenic reactivities. The designed strategy could be immediately translated into any disease in which exosomes are involved. The identification of specific markers and their subsequent association with exosome subtypes, together with the possibility to engineer target-guided exosome-like particles, could represent the key for the effective adoption of exosomes in clinical practice.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c4984f07c16731701e345a94be7a9a0 https://doi.org/10.1039/d1nr06804k Zobrazit plný text záznamu