Effects of concurrent training on oxidative stress and insulin resistance in obese individuals
| Autor: | Leandro Silva de Lemos, Niara da Silva Medeiros, Alana Schraiber Colato, Caroline Dani, Gilson Pires Dorneles, Thiago Rozales Ramis, Fabiana Guichard de Abreu, Cláudia Funchal |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Blood Glucose Male Aging medicine.medical_specialty Article Subject medicine.medical_treatment Protein oxidation medicine.disease_cause Biochemistry Body Mass Index Insulin resistance Internal medicine medicine TBARS Humans Insulin Obesity lcsh:QH573-671 Exercise chemistry.chemical_classification Glutathione Peroxidase lcsh:Cytology business.industry Glutathione peroxidase Cell Biology General Medicine Middle Aged medicine.disease Oxidative Stress Endocrinology chemistry Female Insulin Resistance business Body mass index Oxidative stress Research Article |
| Zdroj: | Oxidative Medicine and Cellular Longevity Oxidative Medicine and Cellular Longevity, Vol 2015 (2015) |
| ISSN: | 1942-0994 |
| Popis: | Obesity is associated with insulin resistance (IR) and increased oxidative stress. Thus, the present study aimed to evaluate anthropometric parameters, IR, and oxidative stress in obese individuals subjected to two types of concurrent training at the same intensity but differing in frequency. Accordingly, 25 individuals were divided into two groups: concurrent training 1 (CT1) (5 d/wk) and concurrent training 2 (CT2) (3 d/wk), both with moderate intensity. Anthropometric parameters, IR, and oxidative stress were analyzed before and after 26 sessions of training. Both groups had reduced body weight and body mass index (P<0.05), but only CT1 showed lower body fat percentage and increased basal metabolic rate (P<0.05). Moreover, CT1 had increased HOMA-IR and decreased protein damage (carbonyl level), and CT2 had decreased HOMA-IR and increased lipid peroxidation (TBARS level) (P<0.05). On the other hand, both training protocols reduced the GPx activity. It can be concluded that both types of concurrent training could be an alternative for lowering body weight and BMI. Also, it was observed that concurrent training, depending on the frequency, can contribute to reducing body fat, oxidative damage (protein oxidation), and IR but can induce oxidative damage to lipids. More studies are needed to elucidate the mechanisms involved. |
| Databáze: | OpenAIRE |
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