Hypogeusia and zinc depletion in chronic dialysis patients
| Autor: | B W Goddard, Atkin-Thor E, R L Stephen, W J Kolff, J O'Nion |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Adult
medicine.medical_specialty Taste Calorie medicine.medical_treatment Medicine (miscellaneous) Placebo Taste Disorders Renal Dialysis Internal medicine medicine Humans Aged Nutrition and Dietetics business.industry Hypogeusia Hair analysis Middle Aged medicine.disease Zinc Endocrinology Poor Appetite Zinc deficiency Hemodialysis medicine.symptom Energy Intake business Hair |
| Zdroj: | The American Journal of Clinical Nutrition. 31:1948-1951 |
| ISSN: | 0002-9165 |
| DOI: | 10.1093/ajcn/31.10.1948 |
| Popis: | Dialysis patients generally have a poor appetite, do not enjoy eating, and complain of food, particularly protein, as being disagreeable. Twenty dialysis patients with the above symptoms were tested for taste acuity, serum zinc (Zn), Zn concentrations in hair samples (intracellular Zn), and daily caloric intake. A double-blind, cross-over study was instituted using a Zn supplement and a placebo. After supplementation with Zn, taste acuity markedly improved in 95% of patients and Zn concentrations in hair increased in 85% of patients. The patients' appetites were improved; the average caloric intake increased by 675 kcal/day, and intolerance to protein diminished. In addition 10 normal control subjects were studied pre- and post-Zn supplementation for fasting blood glucose, serum Zn levels, and hair Zn concentration. Side effects were noted, and these usually correlated with elevated serum Zn levels and were minimized or disappeared with decrease in dosage or cessation of therapy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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