Urinary tract infections in a Tertiary Hospital in Abuja, Nigeria
Autor: | Kenneth Iregbu, PI Nwajiobi-Princewill |
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Rok vydání: | 2013 |
Předmět: |
medicine.medical_specialty
Pediatrics Imipenem medicine.drug_class business.industry General Chemical Engineering Urinary system Antibiotics Urine Urinary tract infection National Hospital Abuja antibiotic Medical microbiology Age groups Amikacin medicine Prospective cohort study business medicine.drug |
Zdroj: | African Journal of Clinical and Experimental Microbiology; Vol 14, No 3 (2013); 169-173 |
ISSN: | 1595-689X |
Popis: | Background : Urinary tract infections (UTIs) are among the most common bacterial infections. In uncomplicated cases the infection is easily treated with a course of antibiotic, but there is increased resistance to many of these antibiotics. Objective : To determine the profile of UTI among patients using National Hospital Abuja and the antibiotic susceptibility profile of isolated uropathogens. Methods : This prospective study was carried out at the department of Medical Microbiology of National Hospital, Abuja over a period of three years (January 2010 – December 2012). A total of 6763 urine samples were analyzed for age, gender, distribution, yield and antibiotics sensitivity. Results : Of 6763 urine samples, 885 (13.1%) yielded uropathogens, with the highest percentage yield in the below one year and above 57 years age groups. The mean age was 33.9 years and modal group was 25 -32 years. The most common isolates were Escherichia coli 323 (37%) and Klebsiella spp 202 (25%). Although more infections occurred in outpatients than inpatients, the rate was more with inpatients (36% vs 11%). 97% of Klebsiella spp, 89% of E col i and 83% of P.aeruginosa were sensitive to imipenem, while their respective sensitivities to amikacin were 65%, 98% and 96% Most isolates showed high levels of resistance to many other antibiotics tested. Conclusion : High levels of resistance exist among uropathogens in our study area. This calls for regular surveillance and improved antibiotic stewardship. Keywords : Urinary tract infection, National Hospital Abuja, antibiotic |
Databáze: | OpenAIRE |
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