Urinary tract infections in a Tertiary Hospital in Abuja, Nigeria

Autor: Kenneth Iregbu, PI Nwajiobi-Princewill
Rok vydání: 2013
Předmět:
Zdroj: African Journal of Clinical and Experimental Microbiology; Vol 14, No 3 (2013); 169-173
ISSN: 1595-689X
Popis: Background : Urinary tract infections (UTIs) are among the most common bacterial infections. In uncomplicated cases the infection is easily treated with a course of antibiotic, but there is increased resistance to many of these antibiotics. Objective : To determine the profile of UTI among patients using National Hospital Abuja and the antibiotic susceptibility profile of isolated uropathogens. Methods : This prospective study was carried out at the department of Medical Microbiology of National Hospital, Abuja over a period of three years (January 2010 – December 2012). A total of 6763 urine samples were analyzed for age, gender, distribution, yield and antibiotics sensitivity. Results : Of 6763 urine samples, 885 (13.1%) yielded uropathogens, with the highest percentage yield in the below one year and above 57 years age groups. The mean age was 33.9 years and modal group was 25 -32 years. The most common isolates were Escherichia coli 323 (37%) and Klebsiella spp 202 (25%). Although more infections occurred in outpatients than inpatients, the rate was more with inpatients (36% vs 11%). 97% of Klebsiella spp, 89% of E col i and 83% of P.aeruginosa were sensitive to imipenem, while their respective sensitivities to amikacin were 65%, 98% and 96% Most isolates showed high levels of resistance to many other antibiotics tested. Conclusion : High levels of resistance exist among uropathogens in our study area. This calls for regular surveillance and improved antibiotic stewardship. Keywords : Urinary tract infection, National Hospital Abuja, antibiotic
Databáze: OpenAIRE