The development of the amnion in mice and other amniotes
| Autor: | Chuva de Sousa Lopes, Susana M, Roelen, Bernard A J, Lawson, Kirstie A, Zwijsen, An, Anatomie en fysiologie, Voortplanting paard, CS_Cancer |
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| Přispěvatelé: | Anatomie en fysiologie, Voortplanting paard, CS_Cancer |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
clonal analysis
PLACENTATION Agricultural and Biological Sciences(all) ORIGIN Biochemistry Genetics and Molecular Biology(all) Gastrulation FATE extraembryonic membranes YOLK-SAC MOUSE EMBRYOS Biochemistry General Biochemistry Genetics and Molecular Biology Mesoderm Mice DIFFERENTIATION Animals amniotes GASTRULATION amniochorionic fold General Agricultural and Biological Sciences RHYTHMIC CONTRACTIONS STEM-CELLS Genetics and Molecular Biology(all) amnion mouse gastrulation |
| Zdroj: | Philosophical Transactions of the Royal Society B: Biological Sciences, 377(1865). ROYAL SOC Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 377(1865), 1. NLM (Medline) PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES |
| ISSN: | 0962-8436 1471-2970 |
| Popis: | The amnion is an extraembryonic tissue that evolutionarily allowed embryos of all amniotes to develop in a transient and local aquatic environment. Despite the importance of this tissue, very little is known about its formation and its molecular characteristics. In this review, we have compared the basic organization of the extraembryonic membranes in amniotes and describe the two types of amniogenesis, folding and cavitation. We then zoom in on the atypical development of the amnion in mice that occurs via the formation of a single posterior amniochorionic fold. Moreover, we consolidate lineage tracing data to better understand the spatial and temporal origin of the progenitors of amniotic ectoderm, and visualize the behaviour of their descendants in the extraembryonic–embryonic junctional region. This analysis provides new insight on amnion development and expansion. Finally, using an online-available dataset of single-cell transcriptomics during the gastrulation period in mice, we provide bioinformatic analysis of the molecular signature of amniotic ectoderm and amniotic mesoderm. The amnion is a tissue with unique biomechanical properties that deserves to be better understood. This article is part of the theme issue ‘Extraembryonic tissues: exploring concepts, definitions and functions across the animal kingdom’. |
| Databáze: | OpenAIRE |
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