Failure of antipsychotic drug dose to explain abnormal diurnal weight gain among 129 chronically psychotic inpatients
| Autor: | W. Victor R. Vieweg, Glenn R. Yan, P. L. Hundley, L. S. Godleski |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
Adult
Male Phenytoin medicine.medical_specialty Mean arterial pressure Chlorpromazine medicine.medical_treatment Neurocognitive Disorders Physiology Blood Pressure Sex Factors Internal medicine medicine Humans Pulse Antipsychotic Biological Psychiatry Morning Pharmacology Inpatients Mood Disorders business.industry Body Weight Age Factors Carbamazepine Middle Aged Circadian Rhythm Blood pressure Endocrinology Psychotic Disorders Chronic Disease Schizophrenia Female medicine.symptom business Weight gain Antipsychotic Agents medicine.drug |
| Zdroj: | Progress in Neuro-Psychopharmacology and Biological Psychiatry. 13:709-723 |
| ISSN: | 0278-5846 |
| DOI: | 10.1016/0278-5846(89)90059-6 |
| Popis: | 1. 1. The diurnal weight gain was found to be abnormal among 129 chronically psychotic inpatients. 2. 2. The patients were weighed at 7 a.m. and 4 p.m. weekly for three weeks. We normalized the diurnal weight gain (NDWG) as a percentage by subtracting the 7 a.m. weight from the 4 p.m. weight, multiplying the difference by 100, and then dividing the result by the 7 a.m. weight. 3. 3. NDWG was 2.2 ± 1.5 percent for 87 male patients compared (p < .0001) with .53 ± .41 for 14 male controls. 4. 4. NDWG was 1.8 ± 1.0 percent for 42 female patients compared (p < .0001) with .49 ± .30 for 15 female controls. 5. 5. Seventy percent of male and female patients had NDWG values greater than two standard deviations above the mean values of controls. 6. 6. Differences in age, sex, morning weight, antipsychotic drugs, lithium, carbamazepine, phenytoin, blood pressure, and pulse did not explain these findings. |
| Databáze: | OpenAIRE |
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