Retinal blood flow in diabetic children and adolescents
| Autor: | Holger Kiesewetter, Sebastian Wolf, Sitzmann Fc, Friedrich Jung, Bernd Bertram, Martin Reim, K. Schulte |
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| Rok vydání: | 1991 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Eye disease Video Recording Ophthalmoscopy Cellular and Molecular Neuroscience chemistry.chemical_compound Retinal Diseases Diabetes mellitus Ophthalmology medicine Humans Fluorescein Angiography Child Glycemic Glycated Hemoglobin Diabetic Retinopathy medicine.diagnostic_test business.industry Retinal Vessels Retinal medicine.disease Fluorescein angiography Aneurysm Sensory Systems Surgery Diabetes Mellitus Type 1 chemistry Angiography Female business Blood Flow Velocity Retinopathy |
| Zdroj: | Graefe's Archive for Clinical and Experimental Ophthalmology. 229:336-340 |
| ISSN: | 1435-702X 0721-832X |
| DOI: | 10.1007/bf00170691 |
| Popis: | A total of 209 diabetic children and adolescents aged 6-17 years (mean, 12.6 +/- 2.3 years) were examined by ophthalmoscopy, video fluorescein angiography and hemoglobin (HbA1c) test. Microaneurysms were found in 26% of the children (ophthalmoscopy, 11%; angiography, 23%). The prevalence of retinopathy was 16% in patients aged 6-10 years, 27% in those aged 11-13 years and 36% in those aged 14-17 years. Only five diabetics aged 11-17 years showed lesions other than microaneurysms (hard exudates, intraretinal hemorrhages or retinal capillar leakage). Retinal blood flow was quantified using video fluorescein angiography. The arm-retina time (ART) and the arteriovenous passage time (AVP) as parameters of the retinal microcirculation were obtained using an image analysing system. The mean value for ART was 9.7 +/- 2.5 s and that for AVP was 1.43 +/- 0.52 s. AVP was significantly shorter in diabetic children and adolescents with good glycemic control (HbA1c, less than 7%; AVP, 1.35 +/- 0.44 s) than in those with bad glycemic control (HbA1c, greater than or equal to 9%; AVP, 1.65 +/- 0.51 s). |
| Databáze: | OpenAIRE |
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