Bioelectrodes for high-channel count and small form factor CMOS neural probes
| Autor: | Luca Berdondini, Fabio Boi, Aziliz Lecomte, Gian Nicola Angotzi, J. F. Ribeiro |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Materials science
Open-circuit voltage business.industry Amplifier 02 engineering and technology Neural engineering 021001 nanoscience & nanotechnology Signal Small form factor 03 medical and health sciences 0302 clinical medicine CMOS Electrode Optoelectronics 0210 nano-technology business 030217 neurology & neurosurgery DC bias |
| Zdroj: | NER 2021 10th International IEEE/EMBS Conference on Neural Engineering (NER) |
| DOI: | 10.1109/ner49283.2021.9441160 |
| Popis: | SiNAPS neural probes enable continuous sub-millisecond neural activity recordings from all integrated electrodes (up to 1024) with a very small form factor implantable device. Key for this achievement was the integration of DC-coupled analog frontends within micrometric active electrode-pixels. Rather than filtering the DC electrode signal component as in conventional AC-coupled frontends, the SiNAPS electrode-pixel circuit operates with a periodic calibration that sets a DC offset compensating open circuit potential (OCP) changes of each electrode. This keeps the in-pixel amplifiers within the operational range. However, for optimal performances this circuit requires minimizing the OCP variability among all integrated electrodes. Here, we show on 4-shanks SiNAPS-probes that this variability can be controlled by the electrode material, structuring process and functionalization. Among the tested bioelectrodes, results show that evaporated platinum (Pt) functionalized with a monolayer of (3-aminopropyl) triethoxysilane (APTES) leads to less than 20 mV DC offset variability across 1024 electrodes. |
| Databáze: | OpenAIRE |
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