Similarity in Joint Function Limitation in Type 3 Von Willebrand Disease and Moderate Haemophilia A

Autor:	Adam Cuker, Suman L. Sood, Barbara A. Konkle, Ara Metjian, Chengbin Wang, Elaine Y. Chiang, J. M. Soucie
Jazyk:	angličtina
Rok vydání:	2013
Předmět:	Adult Male congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty Time Factors Adolescent Haemophilia A Hemorrhage von Willebrand Disease Type 3 Hemophilia A Gastroenterology Article Young Adult Von Willebrand factor Risk Factors hemic and lymphatic diseases Internal medicine Arthropathy medicine Von Willebrand disease Humans Young adult Range of Motion Articular Child Genetics (clinical) Aged Demography biology business.industry Hematology General Medicine Bleed Middle Aged medicine.disease Bleeding diathesis Child Preschool Immunology biology.protein Female Joints business Range of motion Follow-Up Studies
Popis:	Type 3 von Willebrand's disease (VWD) is a rare bleeding diathesis with complete or near complete deficiency of von Willebrand factor (VWF) and low factor VIII (FVIII) levels. In contrast, only FVIII is decreased in haemophilia A (HA). Both disorders are complicated by arthropathy. The purpose of this study was to further clarify the roles of FVIII and VWF: Antigen (VWF:Ag) in joint range of motion (ROM) loss over time. We compared joint ROM loss and other bleeding manifestations in 100 Type 3 VWD subjects (FVIII
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c29fb70cbbb2e59c1a3159b550f40e7 https://europepmc.org/articles/PMC4545639/ Zobrazit plný text záznamu